Surgery to remove the appendix, called appendectomy, is the go-to treatment for patients with appendicitis and is one of the most common surgical procedures in the U.S. However, antibiotic drugs could take the place of surgery for the many patients who have mild cases of appendicitis, according to new research. Researchers in Finland studied more than 500 adults who had uncomplicated appendicitis, meaning their appendixes had not ruptured and they had no signs of infection or other problems in their abdomens.